Note: to be blunt with food or water, to reduce gastrointestinal irritation.
Adult usual dose of oral:
Antipyretic, analgesic, a 0.3-0.6g, 3 times a day, if necessary, every 4 hours 1.
Anti-rheumatic, day 3-5g (acute rheumatic fever can be used to 7 ~ 8g) orally 4 times.
Inhibition of platelet aggregation, there is no clear dosage, most advocate the application of small doses, such as 50-150mg every 24 hours.
Treatment of biliary ascariasis, a 1g, 2-3 times a day, once every 2-3 days; paroxysmal twist pain stop 24 hours after the disabled, and then de-worming treatment.
Pediatric usual dose of oral:
Antipyretic, analgesic, daily according to body surface area 1.5g / square meter, divided into 4 to 6 times a day orally, or each by 5-10mg/kg of weight or each 60mg per year-old, when necessary, 4 to 6 hours, 1 .
Anti-rheumatic, 80 ~ 100mg/kg of body weight daily, 3-4 times a service, such as 1-2 weeks without the efficacy, dosage can be adjusted under the plasma concentration. In some cases need to be increased to 130mg/kg daily.
Children used to mucocutaneous lymph node syndrome (Kawasaki disease), start daily by weight 80-100mg/kg, 3-4 times served hot back 2-3 days later changed to 30mg/kg a day divided into 2-4 during the times service, even service or more in February, thrombocytosis, blood hypercoagulable state, daily 5-10mg/kg, Dayton clothing.
Prevention of thrombosis, atherosclerosis and myocardial infarction: 0.3 / day; prevention of transient ischemic attack, 0.6g each time, 2 times a day.
Treatment of biliary ascariasis: each 1g, 2-3 times a day, even for 2-3 days.
Treatment of X-ray irradiation or radiotherapy-induced diarrhea, per serving, 0.6-0.9g, 4 times a day.
Tinea pedis rule, first with warm water or 1:5000 potassium permanganate solution, washed, and then the product powder spreading surface of the skin, usually 2-4 times more. Time to peak of salicylic acid in the morning administration long, long half-life of the evening the opposite. Reasonable administration of the morning dosage slightly increased. Night plus service time.
Usage of some diseases and the best dosage:
Systemic arterial embolism occurred in brain heart disease prevention valve alone, aspirin is invalid, but in combination with dipyridamole, will enhance the effect of small doses of dipyridamole.
Avoid and glucocorticoids in combination; avoid coumarin anticoagulant drugs, lowering blood sugar drug methotrexate, barbiturates, aniline and other combination.
After meals. American College of Chest Physicians Antithrombotic and Thrombolytic Therapy Association (ACCP) evidence-based guidelines state that the use of
aspirin to prevent myocardial infarction, stroke and vascular death, the patient should be based on condition, the optimal dose.
A large number of clinical trials have shown that the majority of patients, including patients with chronic stable or unstable angina, aspirin 75mg / day can effectively reduce the risk of acute myocardial infarction and death. This dose can be reduced transient cerebral ischemic attack in patients with stroke and death incidence. Europe a stroke prevention studies have shown that a history of transient ischemic attack and stroke in patients with a history of aspirin 25mg, 2 times a day, 50mg / day can reduce the risk of stroke or death. Clinical Practice has proved that even in patients taking higher aspirin doses than the table, will not effect a further increase in the occurrence of side effects is greatly increased. Therefore, in the treatment of various thrombotic diseases, patients should use the smallest effective dose, ie, long-term application of 50-160mg / day, in order to achieve maximum efficacy, minimize side effects, this is the patients taking aspirin the optimal dose.
