WHO -原因不明の急性肝炎- | STEAM英語

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World Health Organization

Multi-Country – Acute, severe hepatitis of unknown origin in children

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原因不明の急性肝炎が世界の子どもたちの間で報告されている、とテレビ等で報道されています。

日本でも症例があるようです。早く原因が解明されることを祈ります。

 

下記はWHOのレポート(抜粋)です。

「原因不明の」は英語ではどのように表現されているでしょう。

 

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Outbreak overview

As of 21 April 2022, at least 169 cases of acute hepatitis of unknown origin have been reported from 11 countries in the WHO European Region and one country in the WHO Region of the Americas (Figure 1).

Cases have been reported in the United Kingdom of Great Britain and Northern Ireland (the United Kingdom) (114), Spain (13), Israel (12), the United States of America (9), Denmark (6), Ireland (<5), The Netherlands (4), Italy (4), Norway (2), France (2), Romania (1), and Belgium (1).

 

Cases are aged 1 month to 16 years old.

Seventeen children (approximately 10%) have required liver transplantation; at least one death has been reported.

 

The clinical syndrome among identified cases is acute hepatitis (liver inflammation) with markedly elevated liver enzymes.

Many cases reported gastrointestinal symptoms including abdominal pain, diarrhoea and vomiting preceding presentation with severe acute hepatitis, and increased levels of liver enzymes (aspartate transaminase (AST) or alanine aminotransaminase (ALT) greater the 500 IU/L) and jaundice.

Most cases did not have a fever.

The common viruses that cause acute viral hepatitis (hepatitis viruses A, B, C, D and E) have not been detected in any of these cases.

International travel or links to other countries based on the currently available information have not been identified as factors.

 

Adenovirus has been detected in at least 74 cases, and of the number of cases with information on molecular testing, 18 have been identified as F type 41.

SARS-CoV-2 was identified in 20 cases of those that were tested.

Furthermore, 19 were detected with a SARS-CoV-2 and adenovirus co-infection.

 

acute hepatitis 急性肝炎

liver enzymes 肝酵素

adenovirus アデノウィルス

jaundice 黄疸

 

Figure 1.

Distribution of cases of acute severe hepatitis of unknown origin by country, as of 23 April 2022.