論文No2443
Shorter corridors can be used for the six-minute walk test in subjects with chronic lung diseases
Laura Gochicoa-Rangel, María C. Ramírez-José, Prysila Troncoso-Huitrón, Mónica Silva-Cerón, ... Luis Torre-Bouscoulet
Respiratory Investigation, Volume 58, Issue 4, July 2020, Pages 255-261
＜背景＞
６分間歩行試験(6-MWT)の主な制限は、検査する施設のすべてが室内で平らな30ｍの廊下を有していないことである。
この研究では、１）慢性肺疾患(CLD)群で30mと15mの廊下の6-MWTの距離の相関、一致度を評価し、
２）２つの距離でSpO2、血圧、検査後１分間後の脈拍の回復(HRR1)、呼吸困難と倦怠感のBorgスケールを比較した。
＜方法＞
前向き横断研究をメキシコの国立呼吸器疾患施設で行った。
慢性肺疾患と健康成人が参加した。
6-MWTの距離は最初のテストが15ｍか30ｍかランダムに割り付けられた。
＜結果＞
90名が参加した.
CLDにおける２つの距離の相関はr= 0.96であった.
6-MWTの差の95%範囲は-73mから+37mであった。
多くの患者は30m廊下の方が長く歩いた。
しかし、CLD群の％予測値は15m廊下の方が3.5%少なかった。
CLD患者の10.5%のみが正常の6-MWT距離と分類された(偽陰性)。
15mと30mとで、SpO2, Borgスケール、BP, HRR1は有意な差がなかった。
＜感想＞
６分間歩行距離を30mの廊下で行っても15mの廊下で行っても、有意な差はなかったようです。
Background
The main limitation of the six-minute walk test (6-MWT) is that not all pulmonary function testing facilities have an indoor flat, 30-m-long corridor. Therefore, this study aimed 1) to evaluate the correlation and agreement of the distances walked in 30-m- vs. 15-m-long corridors by subjects with chronic lung diseases (CLD group) and 2) to compare the levels of oxygen saturation (nSpO2), blood pressure (BP), heart rate recovery at minute one post-exercise (HRR1), and Borg scale scores for dyspnea and fatigue between the two distances walked.
Methods
A prospective, cross-sectional study was conducted at the National Institute of Respiratory Diseases in Mexico City. Subjects with chronic lung diseases and healthy adults were invited to participate. The distance of the 6-MWT was randomly assigned based on whether the first test was in the 15-m or 30-m corridor.
Results
Ninety individuals were included; the correlation in meters walked between the two corridors was r = 0.96 in CLD; the 95% limits of agreement for the 6-MWT ranged from −73 to +37 m. Most subjects walked further in the 30-m corridor (82%); however, the percent predicted values for the CLD group were 3.5% lower for the 15-m corridor than the 30-m corridor. Only 10.5% of the subjects with CLD would have been falsely classified as having a normal 6-MWT (false negative). No significant differences in the nSpO2, Borg scale, BP or HRR1 were found between the two 6-MWT corridor lengths.
Conclusion
The 6-MWT can be performed using a 15-m corridor in subjects with CLD, and the results for the distance walked, HRR1, nSpO2, and Borg scale scores are similar to between the 15-m and 30-m corridors.