【むずむず脚症候群は、シーボ(SIBO)を治療することで良くなる!】 江田証
腸内細菌を正常化し、腸の調子を整えると、むずむず脚症候群が良くなるという報告が2編発表されている。
SIBO(小腸内菌増殖症;Small Intestinal Bacterial Overgrowth)を治療すると、むずむず脚症候群の症状が改善するのだ。
今回の私の新刊にも知られざる「腸とむずむず脚症候群の関係」について詳説した。
SIBO(小腸内菌増殖症;Small Intestinal Bacterial Overgrowth)について勉強してみてほしい。
Antibiotic therapy may improve idiopathic restless legs syndrome: prospective, open-label pilot study of rifaximin, a nonsystemic antibiotic.
②Dig Dis Sci. 2008 May;53(5):1252-6. Epub 2007 Oct 13.
Restless legs syndrome in patients with irritable bowel syndrome: response to small intestinal bacterial overgrowth therapy.
Abstract
BACKGROUND:
Small intestinal bacterial overgrowth (SIBO) occurs in irritable bowel syndrome (IBS) and fibromyalgia. Since restless legs syndrome (RLS) occurs with fibromyalgia, a link between IBS, SIBO, and RLS was studied.
METHODS:
BS patients with abnormal lactulose breath tests received rifaximin 1,200 mg day(-1) for 10 days, followed by tegaserod 3 mg, long-term, and 1 month of zinc 220 mg day(-1) and once-daily probiotic (N = 11) or rifaximin monotherapy (N = 2). IBS symptom improvement was assessed after rifaximin. RLS symptoms, IBS symptoms, and overall IBS global improvement were assessed at last posttreatment visit: 8/10 patients were followed long-term (mean, 139 days; range, 54-450 days).
RESULTS:
Ten of 13 patients exhibited > or =80% improvement from baseline in RLS symptoms. Five maintained complete resolution of RLS symptoms. Global gastrointestinal symptom improvement was great (n = 6), moderate (n = 5), or mild (n = 2).
CONCLUSION:
This study suggests that SIBO associated with IBS may be a factor in some RLS patients and SIBO therapy provides long-term RLS improvement.
医療法人社団信証会 江田クリニック 院長 江田証
