どうも 例のメチルコバラミンの副作用についての
スレッドで
自分と似てるような経過の人がいるかんじ。。
1年以上経って 95パーセントの回復を実感しているという
記述かな。。
＞
I do not have PA but came here to express my experiences with taking a single dose of methylcobalmin (1000 mcg). I've trolled around the internet for months now gathering anecdotal experiences from people, and this thread seems to have a few people who can confirm in very similar detail of the extreme reactions I had.
I didn't have any major problems before taking methylcobalmin, but I did get it because I was feeling a lack of energy and thought it was harmless (water soluble, can't overdose people say on the internet!).
The symptoms didn't kick in initially and took about 24-30 hrs to feel the effects. I woke up after that time period and had a general feeling of unease during my sleep, which was very unusual, but I brushed it off and went about my day. Something was off with my vision too, it was difficult to track objects, read text and my vision was very surreal looking and vivid. I disregarded that too as it wasn't debilitating but was noticable.
Later that evening I had a series of panicked attacks. I had never had them before (other than from smoking marijuana, which I have only tried a few times). That night was awful sleep. Very wired and full of dark, creepy energy. I also had to urinate almost 10 times during the evening.
My mental state from here just kept getting worse. I would have days long, never-ending panick attacks. The anxiety was unlike anything I have ever experienced, it was dark and creepy feeling with dread.
After two weeks or so, some or the symptoms diminished like the urination, gastrointestinal issues, and extreme panick attacks. Unfortunately, I was left with a bonafide anxiety disorder as diagnosed by a pyschiatrist. I had months of anxiety and derealization and sleep disturbances before I got it under control (with SSRI meds). I also was presented with depressive symptoms (literally had the experience of feeling like nothing, which was a trip).
I don't necessarily believe the B12 caused my current level of anxiety, but the experience kick started me into an anxiety disorder and/or PTSD. Admittedly I have always been anxiety ridden but nothing ever like this, and never felt I needed medical help for it. I had zero reference for these type of emotions and feelings before, so this really hit me hard.
During my investigation and multiple health screenings, nothing abnormal came up other than I have MTHFR A1298C and some other "impairments" like COMT and MAO.
My belief is these SNPs are important and may explain my extreme symptoms -- but the people and communities behind these issues are not fully aware of the science. There is so much confusion and hearsay on the internet.
I would recommend avoiding high doses of these "methylated" vitamins and stick to what's known in terms or B12 treatments (cyanocobalamin). There is no evidence they're better for you that I am aware of, but I'll let people decide that with your doctor's input. I'm just here to warn you my experience was harrowing and while I have gotten 95 percent better, there were times I wanted to jump off a bridge in a very literal sense. I'm still not out of the woods more than a year later and am relying on meds which has its own separate issues.
Be careful with these supplements and take these methylation experts' opinions' with an incredibly open mind and question their conclusions with the utmost skepticism.