富山大学の論文です。 | めまい診療 

富山大学の論文です。

一般に低音難聴ではメニエール病と類似した病態がいわれていますが
低音難聴でも高音難聴でもメニエール病への移行率は変わらなかった。
184例の低音難聴で177例は難聴のみであった。そのうち83例はめまいはなく反復性の難聴であった。このうち15例は後でめまい発作を起こした。94例は単発であった。7例のうち3例はめまいと反復性の難聴をおこしそのうち2例はメニエール病と診断された。
メニエール病や反復性の低音難聴はそれ以外の症例に比べて蝸電図でのAP/SPが高値であった。
つまり低音難聴でメニエール病という診断になるのは1%であるということで、低音難聴でも初発時にめまいを伴わないものでも10%は後にめまい発作を起こす可能性がある。しかしこれはメニエール病になるわけではないようである。

Prognosis of low-tone sudden deafness - does it inevitably progress to Meniere's disease?
Junicho M,Aso S,Fujisaka M,Watanabe Y
ACTA OTO-LARYNGOLOGICA
2008; 128(3): 304-308
Conclusion. We conclude that not all low-tone sudden deafness (SD) patients suffered from endolymphatic hydrops even if they had vertigo attack at the onset and that electrocochleography (ECochG) was a useful prognostic tool. Objectives. To investigate whether low-tone SD was a precursor of Meniere's disease and whether patients with low-tone SD suffered from endolymphatic hydrops. Patients and methods. This was a retrospective case review in the university hospital. A total of 184 patients with low-tone SD were divided into two groups with single and recurrent episodes. The progress, follow-up audiograms, and ECochG results of the patients were reviewed and compared with those of patients with high-tone SD and Meniere's disease. Results. In all, 83 of 177 patients with low-tone SD unaccompanied by vertigo had recurrent hearing loss; 15 of the 83 developed vertiginous attacks. The remaining 94 patients had a single episode. Three of the seven patients with low-tone SD accompanied by vertigo had recurrent hearing loss; two of the three were subsequently confirmed to have Meniere's disease. The other four had a single episode. No difference in rate of progress from SD to Meniere's disease was observed among the low-tone and the high-tone SD groups. The average -SP/AP of each group with a single episode is smaller than that of other groups with recurrent episodes and Meniere's disease.