VZV

incubation period 10-21days (gen. 14-17days)
contactで感染する確率 70-90%
感染性があるのはrashが出る48時間前からrashが消える(crusted)まで

Exposure criteria
continuous household contact
playmate for > 1hr indoor
hospital contact
Mother with onset of chicken pox <5days before or <2days delivery

High risk person
(IC children, healthy adolescent(15>yrs) and adult, pregnant women,
Newborn of mother with onset of above mentioned, hospitalized preme infant)

VZIG is indicated in high-risk persons exposed to VZV.
within 96hrs of exposure (preferably within 72hrs)

It may not prevent infection but reduce the disease severity.

Post-exposure prophylaxis は96hr以内のVZIGかacyclovir.