The National Institutes of Health (NIH) have been forced to halt a study involving a potential vaccine for HIV, after finding that it was ineffective.regarding the decision on Thursday, the NIH stated that the vaccine also proved ineffective at reducing the amount of HIV found in the blood of those already infected.
The study, designated HVTN 505, had been going on for almost four years, and involved some 2,504 volunteers in 19 different cities. All of the participants were either homosexual men or transgender men who only have sex with other men.
Here is some of the key information that emerged on Thursday regarding the NIH's decision to halt its study involving this particular HIV vaccine.
* The study was being conducted through the HIV Vaccine Trials Network (HVTN), which is funded by the National Institute of Allergy and Infectious Diseases (NIAID).
* The number of volunteers given the actual vaccine versus those that were given a placebo were nearly equal, with 1,250 participants given the vaccine and 1,244 given the placebo.
* According to the NIH statement, structures from all three subtypes of HIV were included in the vaccine. Unlike some vaccinations designed to protect from other diseases, this HIV vaccine did not contain either live or weakened strains of HIV, so could not cause the disease itself.
* The vaccine trial was reportedly halted after an independent data and safety monitoring board (DSMB) that reviewed the study recommended it.
* The news of the trial's failure to produce an effective HIV vaccine disappointed both those involved with the study and outside organizations. Mitchell Warren, who is the executive director for AVAC: Global Advocacy for HIV Protection, issued a statement to the media on Thursday, in which he said that "the trial has provided a clear, swift answer about a specific vaccine strategy." Warren expressed hope for future developments, however, noting that "it's not the answer we hoped for, but the search doesn't end here,"
*the NIH will continue to monitor the health of study participants, in order to follow up on the initial research data.
* Several other vaccine trials are either already in progress or planned. One of the most promising may involve the follow-up on the results of a 2009 study in Thailand, that produced results strong enough to encourage researchers that it may be possible to find a vaccine to protect people against HIV infection in the near future.
Vanessa Evans is a musician and freelance writer based in Michigan, with a lifelong interest in health and nutrition issues.http://en.netlog.com/sanfordmcwhorter/blog/blogid=24590287
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