【番外編】父方祖父系のFACTIDS検査 | Kuma the bearのブログ

Kuma the bearのブログ

ジェノグラフィックプロジェクトに参加し、遺伝子を検査することから自分のルーツを探っています。他には気まぐれに放射線量を測定し、その結果をアップしています。

とりあえず、父方祖父系の検査は残り多くはないのですが、実質この検査は遺伝子の検査ではあるものの、もともとのジェノグラフィックプロジェクトからみたら、番外編的な検査です。説明にも書いてあるのですが、医学的な根拠としてはあまり使えず、要するに若干の話題作り程度の意味あいでの検査ということです。


Alcohol Flush Reaction(アルコールによる反応)

A condition in which the body cannot break down ingested alcohol completely. Flushing, after consuming one or two alcoholic beverages, includes a range of symptoms: nausea, headaches, light-headedness, an increased pulse, occasional extreme drowsiness, and occasional skin swelling and itchiness. These unpleasant side effects often prevent further drinking that may lead to further inebriation, but the symptoms can lead to mistaken assumption that the people affected are more easily inebriated than others.


Avoidance of Errors(間違えからの回避)

We are often angry at ourselves because we are unable to learn from certain experiences. Numerous times we have made the wrong decision and its consequences were unfavorable. But the cause does not lie only in our thinking. A mutation in a specific gene can also be responsible, because it can cause a smaller number of dopamine receptors. They are responsible for remembering our wrong choices, which in turn enables us to make better decisions when we encounter a similar situation.


Back Pain(背痛)

Lumbar disc disease is the drying out of the spongy interior matrix of an intervertebral disc in the spine. Many physicians and patients use the term lumbar disc disease to encompass several different causes of back pain or sciatica. A study of Asian patients with lumbar disc disease showed that a mutation in the CILP gene increases the risk of back pain.


Bitter Taste perception(苦みを感じる味覚)

There are several genes that are responsible for bitter taste perception – we test 3 of them. Different variations of this gene affect ability to detect bitter compounds. About 25% of people lack ability to detect these compounds due to gene mutations. Are you like them? Maybe you don't like broccoli, because it tastes too bitter?

Caffeine metabolism(カフェイン代謝)

According to the results of a case-control study reported in the March 8, 2006 issue of JAMA, coffee is the most widely consumed stimulant in the world, and caffeine consumption has been associated with increased risk for non-fatal myocardial infarction. Caffeine is primarily metabolized by the cytochrome P450 1A2 in the liver, accounting for 95% of metabolism. Carriers of the gene variant *1F allele are slow caffeine metabolizers, whereas individuals homozygous for the *1A/*1A genotype are rapid caffeine metabolizers.

Earwax Type(耳垢の形状)

Whether your earwax is wet or dry is determined by a mutation in a single gene, which scientists have discovered. Wet earwax is believed to have uses in insect trapping, self-cleaning and prevention of dryness in the external auditory canal of the ear. It also produces an odor and causes sweating, which may play a role as a pheromone.

Freckling(しみ、そばかす)

Freckles can be found on anyone no matter what the background. However, having freckles is genetic and is related to the presence of the dominant melanocortin-1 receptor MC1R gene variant.


Longevity (長寿)

Researchers at Harvard Medical School and UC Davis have discovered a few genes that extend lifespan, suggesting that the whole family of SIR2 genes is involved in controlling lifespan. The findings were reported July 28, 2005 in the advance online edition of Science.


Male Pattern Baldness (男性型脱毛症)

Researchers at McGill University, King's College London and GlaxoSmithKline Inc. have identified two genetic variants in Caucasians that together produce an astounding sevenfold increase of the risk of male pattern baldness. Their results were published in the October 12, 2008 issue of the Journal of Nature Genetics.

Muscle Performance (筋肉の能力)

A team of researchers, led by scientists at Dartmouth Medical School and Dartmouth College, have identified and tested a gene that dramatically alters both muscle metabolism and performance. The researchers say that this finding could someday lead to treatment of muscle diseases, including helping the elderly who suffer from muscle deterioration and improving muscle performance in endurance athletes.

Nicotine dependence (ニコチン依存症)

In 2008, University of Virginia Health System researchers have identified a gene associated with nicotine dependence in both Europeans and African Americans.


実際にはいろいろと書いてあるのですが、とりあえず題名だけを日本語にしてあります。基本的には一見医学的ですが、どちらかといえば興味的なものばかりかなと思っています。