世界の一流医学雑誌「ランセット」に2001年に掲載された「たばことうつ病」に関する英語論文です。うつ病にかかった患者さんを調べたところ、禁煙を心がけた人の方がたばこを吸い続けている人より、うつ病になる確率が高かったとあります。簡単に言えば、たばこを吸っていたが辞めようと努力した人がうつ病の人に多かったと解釈できます。うつ病になりたくなければタバコを吸った方がいいとは、けっして書いてありません。ただ、吸い続けている人よりうつ病になりやすいということは、ストレス解消法としてたばこは役にたっているのかもしれません。だから吸ってもよいとは書いてありません。さらにご関心のある方は検索を、142. Lancet. 2001 Jun 16;357(9272):1929-32.
※参考文献
: Smokers with a history of major depression who attempt to stop
smoking have a higher risk of failure than non-depressed smokers
Lancet. 2001 Jun 16;357(9272):1929-32.
Smoking cessation and the course of major depression: a follow-up study.
Glassman AH(1), Covey LS, Stetner F, Rivelli S.
Author information:
(1)Department of Clinical Psychopharmacology, New York State Psychiatric
Institute, 1051 Riverside Drive, 10032, New York, NY, USA. ahg1@columbia.edu
Comment in
Lancet. 2001 Jun 16;357(9272):1900-1.
Lancet. 2001 Sep 22;358(9286):1011.
Lancet. 2001 Sep 22;358(9286):1011-2.
BACKGROUND: Smokers with a history of major depression who attempt to stop
smoking have a higher risk of failure than non-depressed smokers. Anecdotal and
post-hoc data suggest that those who successfully abstain are at increased risk
of depression compared with individuals who continue to smoke. However, these
studies confound effects of abstinence and history of depression. We aimed to
assess whether there is an increased risk of depression and for how long that
increase lasts.
METHODS: We enrolled 100 smokers (>1 pack per day) with a history of major
depression, but who were currently free from major depression and had not been on
antidepressant medicine for at least 6 months, in a 2-month smoking-cessation
trial. The primary outcome was recurrence of major depression, which we assessed
by structured clinical interviews 3 and 6 months after the end of treatment. We
verified smoking status by serum-sample cotinine concentrations.
FINDINGS: 76 participants (42 successful abstainers, 34 smokers) were followed
13 abstainers and two smokers had an episode of major depression (odds ratio
7.17 [95% CI 1.5-34.5]; Kaplan-Meier survival curve, log-rank statistic 9.11
[p=003]). Risk of major depression was similar between the first and second 3
※参考文献
: Smokers with a history of major depression who attempt to stop
smoking have a higher risk of failure than non-depressed smokers
Lancet. 2001 Jun 16;357(9272):1929-32.
Smoking cessation and the course of major depression: a follow-up study.
Glassman AH(1), Covey LS, Stetner F, Rivelli S.
Author information:
(1)Department of Clinical Psychopharmacology, New York State Psychiatric
Institute, 1051 Riverside Drive, 10032, New York, NY, USA. ahg1@columbia.edu
Comment in
Lancet. 2001 Jun 16;357(9272):1900-1.
Lancet. 2001 Sep 22;358(9286):1011.
Lancet. 2001 Sep 22;358(9286):1011-2.
BACKGROUND: Smokers with a history of major depression who attempt to stop
smoking have a higher risk of failure than non-depressed smokers. Anecdotal and
post-hoc data suggest that those who successfully abstain are at increased risk
of depression compared with individuals who continue to smoke. However, these
studies confound effects of abstinence and history of depression. We aimed to
assess whether there is an increased risk of depression and for how long that
increase lasts.
METHODS: We enrolled 100 smokers (>1 pack per day) with a history of major
depression, but who were currently free from major depression and had not been on
antidepressant medicine for at least 6 months, in a 2-month smoking-cessation
trial. The primary outcome was recurrence of major depression, which we assessed
by structured clinical interviews 3 and 6 months after the end of treatment. We
verified smoking status by serum-sample cotinine concentrations.
FINDINGS: 76 participants (42 successful abstainers, 34 smokers) were followed
13 abstainers and two smokers had an episode of major depression (odds ratio
7.17 [95% CI 1.5-34.5]; Kaplan-Meier survival curve, log-rank statistic 9.11
[p=003]). Risk of major depression was similar between the first and second 3