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Antimicrobial activity of essential oils against Helicob acter pylori.

Ohno T, Kita M, Yamaoka Y, Imamura S, Yamamoto T, Mitsufuji S, Kodama T, Kashima K, Imanishi J. Third D epartment of Internal Medicine, Kyoto Prefectural Univ ersity of Medicine, Kyoto, 602-8566, Japan.

Abstract

BACKGROUND: Helicobacter pylori is an important pat hogen responsible for gastroduodenal diseases in hu mans. Although the eradication of H. pylori using anti biotics often improves gastroduodenal diseases, resis tance to the antibiotics is emerging.

MATERIALS AND METHODS: The antimicrobial effect of essential oils and the development of resistance to the essential oils were evaluated in vitro and in vivo.

RESULTS: Thirteen essential oils used in this study co mpletely inhibited the growth of H. pylori in vitro at a c oncentration of 0.1% (v/v). Cymbopogon citratus (Lem ongrass) and Lippia citriodora (Lemon verbena) were bactericidal against H. pylori at 0.01% at pH 4.0 and 5. 0. Resistance to Lemongrass did not develop even aft er 10 sequential passages, whereas resistance to clari thromycin developed under the same conditions. In in vivo studies, the density of H. pylori in the stomach of mice treated with Lemongrass was significantly reduc ed compared with untreated mice.

CONCLUSIONS: These results demonstrate that the es sential oils are bactericidal against H. pylori without th e development of acquired resistance, suggesting that essential oils may have potential as new and safe age nts for inclusion in anti-H. pylori regimens.

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· 4 drops Digestive Blend
· 4 drops Lemongrass
· 4 drops Frankincense

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6滴のダイジェストゼン(ゼンジェスト)
6滴のペパーミント をカプセルに入れて1日に2回取ると1週間で回復して 胃酸のコントロール出来るようになりもう1年も再発してないそうです