Dynamiker Cryptococcal Antigen Lateral Flow Assay(LFA)
The 2022 WHO guidelines show that cryptococcal meningitis is one of the most common opportunistic infections among HIV-infected people, especially in patients with advanced AIDS.
It is used for the detection of capsular polysaccharide antigens of Cryptococcus species complex (Cryptococcus neoformans and Cryptococcus gattii) in human ssamples. This cryptococcus lateral flow assay can be used as a screening diagnosis for cryptococcal meningitis.
Specification
|
Catalogue |
DNK-1411-1 |
|
Method |
LFA |
|
Specification |
40/50 tests |
|
Sample |
Serum/CSF |
|
Storage |
2-30℃ |
Guideline
WHO guidelines for the Diagnosis, Prevention, and Management of Cryptococcal Disease in Hiv-Infected Adults, Adolescents, and Children, 2018
Screening for cryptococcal antigen followed by preemptive antifungal therapy among cryptococcal antigen-positive people to prevent the development of invasive cryptococcal disease is recommended before initiating or reinitiating ART for adults and adolescents living with HIV who have a CD4 cell count<100 cells/mm3 (strong recommendation; moderate-certainty evidence) and may be considered at a higher CD4 cell count threshold of <200 cells/mm3 (conditional recommendation; moderate-certainty evidence).
Clinical Performance
Evaluation of the new Dynamiker cryptococcal antigen Lateral Flow Assay (LFA) in comparison with IMMY LFA and Meridian latex agglutination test. Poster no 1197.
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CSF cryptococcal antigen test can be performed rapidly with the lateral flow assay method, which enables on-site detection without requiring complex laboratory equipment. This test is recommended for routine screening among people living with HIV who have a CD4 cell count below 100 cells/mm3, helping to identify cryptococcal infection early before the onset of clinical symptoms. For commercial inquiries about customized csf cryptococcal antigen testing reagents or to obtain the latest product quotation, please contact our sales team via the contact information listed on our official website.
Aspergillus galactomannan antigen positive results often indicate the presence of invasive aspergillosis, a life-threatening fungal infection that commonly occurs in immunocompromised patients including organ transplant recipients, patients receiving long-term immunosuppressive therapy and patients with hematological malignancies. To further confirm the diagnosis, clinicians usually need to combine the test results with imaging findings such as chest CT scans and clinical symptoms of the patient, to avoid misdiagnosis caused by possible false positive results. If you need technical support for the interpretation of test results or supporting documents for clinical research applications, you can contact our technical support team at XX.
