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The subnuclear localization of the h l(3)mbt protein in interphase nuclei is reminiscent of the speckled distribution of the PcG louis vuitton outlet uk proteins. To determine whether h l(3)mbt protein colocalizes with PcG proteins, we performed a double labeling experiment with anti h l(3)mbt antibody and the monoclonal antibody F6 (Alkema et al., 1997a,b) against Bmi1 protein, which is one of the human PcG proteins and which nike air max sale was shown to be present in a largely overlapping pattern with other PcG proteins. Although both the h l(3)mbt and Bmi1 proteins showed a speckled distribution, they did not colocalize in interphase nuclei (Figure 4d).
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