Diagnóstico prequirúrgico de gliomas difusos en adultos: perspectivas prácticas de radiólogos de Unidades de neurooncología Post-WHO 2021

A Pons-Escoda, C Majos, M Smits, L Oleaga - Radiología, 2024
La Clasificación 2021 de tumores del sistema nervioso central (SNC) por la
Organización Mundial de la Salud (OMS) fue acogida con entusiasmo, aunque al
principio pudo parecer abrumadora. Con el tiempo, hemos comprendido los puntos
clave, y basándonos en nuestra experiencia en Unidades de Neurooncología de
hospitales internacionales, hemos elaborado una guía práctica para radiólogos.
Esta guía esclarece los criterios de clasificación de los gliomas difusos en los …
引用: ‪Reliability of IDH1-R132H and ATRX and/or p53 …‬  編集
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[HTML] Exosome‐transmitted podoplanin promotes tumor‐associated macrophage‐mediated immune tolerance in glioblastoma

M Wu, Y Shi, Y Liu, H Huang, J Che, J Shi, C Xu - CNS Neuroscience & Therapeutics, 2024
Aims Glioblastoma is the most frequent and aggressive primary brain tumor,
characterized by rapid disease course and poor treatment responsiveness. The
abundance of immunosuppressive macrophages in glioblastoma challenges the
efficacy of novel immunotherapy. Methods Bulk RNA‐seq and single‐cell RNA‐seq
of glioma patients from public databases were comprehensively analyzed to illustrate
macrophage infiltration patterns and molecular characteristics of podoplanin (PDPN) …
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[HTML] Deciphering Glioblastoma: Fundamental and Novel Insights into the Biology and Therapeutic Strategies of Gliomas

R Onciul, FM Brehar, C Toader, RA Covache-Busuioc… - Current Issues in Molecular …, 2024
Gliomas constitute a diverse and complex array of tumors within the central nervous
system (CNS), characterized by a wide range of prognostic outcomes and responses
to therapeutic interventions. This literature review endeavors to conduct a thorough
investigation of gliomas, with a particular emphasis on glioblastoma (GBM),
beginning with their classification and epidemiological characteristics, evaluating
their relative importance within the CNS tumor spectrum. We examine the …
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[PDF] Improving Seneca Valley Virus targeted cancer therapy using a peptide prodrug

L Cassin - 2024
If breast cancer is the most common type of cancer worldwide, New Zealand is one of
the countries with the highest incidence rate and the highest inequalities within its
population. With almost 30% more cases of breast cancer diagnosed and over 20%
more death in Māori females in the past year the necessity to find an efficient
treatment is even clearer. New types of cancers have emerged in the past few years
without any effective treatments. Oncolytic virotherapy has emerged as a promising …
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[PDF] Surgical margins in head and neck squamous cell carcinoma: a narrative review

Y Chen, NN Zhong, LM Cao, B Liu, LL Bu - International Journal of Surgery, 2024
Head and neck squamous cell carcinoma (HNSCC), a prevalent and frequently
recurring malignancy, often necessitates surgical intervention. The surgical margin
(SM) plays a pivotal role in determining the postoperative treatment strategy and
prognostic evaluation of HNSCC. Nonetheless, the process of clinical appraisal and
assessment of the SMs remains a complex and indeterminate endeavor, thereby
leading to potential difficulties for surgeons in defining the extent of resection. In this …
引用: ‪A Real-Time Near-Infrared Fluorescence Imaging Method for the …‬  編集
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[HTML] Searching for a cut-off point for p53 immunohistochemistry as evidence of TP53 mutations

I Caliskan, R Lu, CSL Ding, FS de Souza, A Perry… - Free Neuropathology, 2024
Searching for a cut-off point for p53 immunohistochemistry as evidence of TP53
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引用: ‪Immunohistochemistry on IDH 1/2, ATRX, p53 and Ki-67 substitute …