＊先端バイオの中間評価が無事に終了しました。
＊今年度から、複数の分担研究者が加入しました。
＊前半の企業導出は７件です。
これらの成果を中心に発表しました。
＊先端バイオの謝辞の入った論文は65報です。
今日は話す時間がありませんでした。
2021
65. Junko Takei, Teizo Asano, Hiroyuki Suzuki, Mika K. Kaneko, Yukinari Kato.
Epitope mapping of the anti-CD44 monoclonal antibody (C44Mab-46) using alanine-scanning mutagenesis and surface plasmon resonance
Monoclon. Antib. Immunodiagn. Immunother., DOI: 10.1089/mab.2021.0028, 2021 (PDF)
64. Teizo Asano, Hiroyuki Suzuki, Mika K. Kaneko, Yukinari Kato.
Epitope Mapping of a Cancer-specific Anti-podocalyxin Monoclonal Antibody (PcMab-60) using Enzyme-linked Immunosorbent Assay and Surface Plasmon Resonance
Monoclon. Antib. Immunodiagn. Immunother., DOI: 10.1089/mab.2021.0030, 2021 (PDF)
63. Hitomi Sudo, Atsushi B. Tsuji, Aya Sugyo, Mika K. Kaneko, Yukinari Kato, Kotaro Nagatsu, Hisashi Suzuki, Tatsuya Higashi
Preclinical evaluation of podoplanin-targeted al-pha-radioimmunotherapy with the novel antibody NZ-16 for malignant mesothelioma
Cells, 10(10), 2503; https://doi.org/10.3390/cells10102503, 2021 (PDF)
62. Tateyama N, Asano T, Ohishi T, Takei J, Hosono H, Nanamiya R, Tanaka T, Sano M, Saito M, Kawada M, Kaneko MK, Kato Y.
An Anti‐HER2 Monoclonal Antibody H2Mab‐41 Exerts Antitumor Activities in Mouse Xenograft Model using Dog HER2‐overexpressed Cells
Monoclon. Antib. Immunodiagn. Immunother., 40(4), 184–190, DOI: 10.1089/mab.2021.0025, 2021 (PDF)
61. Tateyama N, Nanamiya R, Ohishi T, Takei J, Nakamura T, Yanaka M, Hosono H, Saito M, Asano T, Tanaka T, Sano M, Kawada M, Kaneko MK, Kato Y.
Defucosylated Anti-EGFR Monoclonal Antibody 134-mG2a-f Exerts Antitumor Activities in Mouse Xenograft Models of Dog EGFR-overexpressed Cells
Monoclon. Antib. Immunodiagn. Immunother., 40(4), 177–183, DOI: 10.1089/mab.2021.0022, 2021 (PDF)
60. Asano T, Kaneko MK, Kato Y.
Development of a novel epitope mapping system: RIEDL insertion for epitope mapping method
Monoclon. Antib. Immunodiagn. Immunother., 40(4), 162–167, DOI: 10.1089/mab.2021.0023, 2021 (PDF)
59. Nanamiya R, Sano M, Asano T, Yanaka M, Nakamura T, Saito M, Tanaka T, Hosono H, Tateyama N, Kaneko MK, Kato Y.
Epitope Mapping of an Anti-Human EGFR Monoclonal Antibody (EMab-51) using the REMAP Method
Monoclon. Antib. Immunodiagn. Immunother., 40(4), 149–155, DOI: 10.1089/mab.2021.0010, 2021 (PDF)
58. Junko Takei, Teizo Asano, Tomohiro Tanaka, Masato Sano, Hideki Hosono, Ren Nanamiya, Nami Tateyama, Masaki Saito, Hiroyoshi Suzuki, Hiroyuki Harada, Mika K. Kaneko, Yukinari Kato.
Development of a Novel Anti-HER2 Monoclonal Antibody H2Mab-181 for Gastric Cancer
Monoclon. Antib. Immunodiagn. Immunother., 40(4), 168–176, DOI: 10.1089/mab.2021.0021, 2021 (PDF)
57. Asano T, Kaneko MK, Takei J, Tateyama N, Kato Y.
Epitope Mapping of the Anti-CD44 Monoclonal Antibody (C44Mab-46) Using the REMAP Method
Monoclon. Antib. Immunodiagn. Immunother., 40(4), 156–161, DOI: 10.1089/mab.2021.0012, 2021 (PDF)
56. Sano M, Kaneko MK, Asano T, Kato Y.
Epitope Mapping of an Anti-human EGFR Monoclonal Antibody (EMab-134) using the REMAP Method
Monoclon. Antib. Immunodiagn. Immunother., 40(4), 191–195, DOI: 10.1089/mab.2021.0014, 2021 (PDF)
55. Tanaka T, Asano T, Sano M, Takei J, Hosono H, Nanamiya R, Tateyama N, Kaneko MK, Kato Y.
Epitope Mapping of the Anti-California Sea Lion Podoplanin Monoclonal Antibody PMab-269 using Alanine-scanning Mutagenesis and ELISA
Monoclon. Antib. Immunodiagn. Immunother., 40(4), 196–200, DOI: 10.1089/mab.2021.0017, 2021 (PDF)
54. Asano T, Ohishi T, Takei J, Nakamura T, Nanamiya R, Hosono H, Tanaka T, Sano M, Harada H, Kawada M, Kaneko MK, Kato Y.
Anti-HER3 monoclonal antibody exerts antitumor activity in a mouse model of colorectal adenocarcinoma
Oncol. Rep., 46(2): 173, https://doi.org/10.3892/or.2021.8124, 2021 (PDF)
53. Nanamiya R, Takei J, Asano T, Sano M, Tanaka T, Hosono H, Harada H, Sakai Y, Mizuno T, Suzuki H, Kaneko MK, Kato Y.
Ferret Podoplanin is Detected by PMab-241 in Immunohistochemistry
Monoclon. Antib. Immunodiagn. Immunother.,40(3),134–140, DOI: 10.1089/mab.2021.0016, 2021 (PDF)
52. Nanamiya R, Takei J, Asano T, Tanaka T, Sano M, Nakamura T, Yanaka M, Hosono H, Kaneko MK, Kato Y.
Development of Anti-Human CC Chemokine Receptor 9 Monoclonal Antibodies for Flow Cytometry
Monoclon. Antib. Immunodiagn. Immunother.,40(3), 101–106, DOI: 10.1089/mab.2021.0007, 2021 (PDF)
51. Hosono H, Asano T, Takei J, Sano M, Tanaka T, Kaneko MK, Kato Y
Development of an Anti-Elephant Podoplanin Monoclonal Antibody PMab-265 for Flow cytometry
Monoclon. Antib. Immunodiagn. Immunother., 40(3), 141–145, DOI: 10.1089/mab.2021.0015, 2021 (PDF)
50. Tanaka T, Asano T, Sano M, Takei J, Hosono H, Nanamiya R, Nakamura T, Yanaka M, Harada H, Fukui M, Suzuki H, Uchida K, Nakagawa T, Kato Y, Kaneko MK.
Development of Monoclonal Antibody PMab-269 Against California Sea Lion Podoplanin
Monoclon. Antib. Immunodiagn. Immunother., 40(3), 124–133, DOI: 10.1089/mab.2021.0011, 2021 (PDF)
49. Asano A, Nanamiya R, Takei J, Nakamura T, Yanaka M, Hosono H, Tanaka T, Sano M, Kaneko MK, Kato Y.
Development of Anti-Mouse CC Chemokine Receptor 3 Monoclonal Antibodies for Flow Cytometry
Monoclon. Antib. Immunodiagn. Immunother., 40(3), 107–112, DOI: 10.1089/mab.2021.0009, 2021 (PDF)
48. Nosaki S, Kaneko MK, Tsuruta F, Yoshida H, Kato Y, Miura K.
Prevention of necrosis caused by transient expression in Nicotiana benthamiana by application of ascorbic acid
Plant Physiol., 186(2), 832–835, https://doi.org/10.1093/plphys/kiab102, 2021 (PDF)
47. Kanayama M, Oyama R, Mori M, Taira A, Shinohara S, Kuwata T, Takenaka M, Yoneda K, Kuroda K, Ohnaga T, Kato Y, Tanaka F.
Novel circulating tumor cell‑detection chip combining conventional podoplanin and EGFR antibodies for all histological malignant pleural mesothelioma
Oncol. Lett., 22(1), 522 https://doi.org/10.3892/ol.2021.12783, 22(1), 522, 2021 (PDF)
46. Tanaka T, Ohishi T, Asano T, Takei J, Nanamiya R, Hosono H, Sano M, Harada H, Kawada M, Kaneko MK, Kato Y.
An anti-TROP2 monoclonal antibody TrMab-6 exerts antitumor activity in breast cancer mouse xenograft models
Oncology Reports, 46(1), 132, https://doi.org/10.3892/or.2021.8083, 2021 (PDF)
45. Tamura-Sakaguchi R, Aruga R, Hirose M, Ekimoto T, Miyake T, Hizukuri Y, Oi R, Kaneko M, Kato Y, Akiyama Y, Ikeguchi M, Iwasaki K, Nogi T.
Moving toward generalizable NZ-1 labeling for 3D structure determination with optimized epitope tag insertion
Acta Crystallogr D Struct Biol., 77(Pt 5):645-662, doi: 10.1107/S2059798321002527, 2021 (PDF)
44. Tanaka T, Nanamiya R, Takei J, Nakamura T, Yanaka M, Hosono H, Sano M, Asano T, Kaneko MK, Kato Y*.
(*corresponding author)
Development of Anti-Mouse CC chemokine receptor 8 Monoclonal Antibodies for Flow Cytometry
Monoclon. Antib. Immunodiagn. Immunother.,40(2), 65–70, DOI: 10.1089/mab.2021.0005, 2021 (PDF)
43. Asano T, Nanamiya R, Tanaka T, Kaneko MK, Kato Y*.
(*corresponding author)
Development of anti-human killer cell lectin-like receptor subfamily G member 1 monoclonal antibodies for flow cytometry
Monoclon. Antib. Immunodiagn. Immunother.,40(2), 76–80, DOI: 10.1089/mab.2021.0008, 2021 (PDF)
42. Takei J, Asano T, Nanamiya R, Nakamura T, Yanaka M, Hosono H, Tanaka T, Sano M, Kaneko MK, Harada H, Kato Y*.
(*corresponding author)
Development of Anti-Human T-Cell Immunoreceptor with Ig and ITIM Domains (TIGIT) Monoclonal Antibodies for Flow Cytometry
Monoclon. Antib. Immunodiagn. Immunother.,40(2),71–75, DOI: 10.1089/mab.2021.0006, 2021 (PDF)
41. Sayama Y, Kaneko MK, Takei J, Hosono H, Sano M, Asano T, Kato Y.
Establishment of a novel anti-TROP2 monoclonal antibody TrMab-29 for immunohistochemical analysis
Biochem Biophys Rep.,25, 100902, https://doi.org/10.1016/j.bbrep.2020.100902, 2021 (PDF)
40. Sayama Y, Kaneko MK, Kato Y.
Development and characterization of TrMab-6, a novel anti-TROP2 monoclonal antibody for antigen detection in breast cancer
Mol Med Rep., 23(2), article number-92, https://doi.org/10.3892/mmr.2020.11731, 2021 (PDF)
2020
39. Kamoto S, Shinada M, Kato D, Yoshimoto S, Ikeda N, Tsuboi M, Yoshitake R, Eto S, Hashimoto Y, Takahashi Y, Chambers J, Uchida K, Kaneko MK, Fujita N, Nishimura R, Kato Y, Nakagawa T.
Phase I/II Clinical Trial of the Anti-Podoplanin Monoclonal Antibody Therapy in Dogs with Malignant Melanoma
Cells, 9(11), 2529; https://doi.org/10.3390/cells9112529, 2020 (PDF)
38. Kaneko MK, Ohishi T, Takei J, Sano M, Nakamura T, Hosono H, Yanaka M, Asano T, Sayama Y, Harada H, Kawada M, Kato Y.*
(*corresponding author)
The Anti-EpCAM monoclonal antibody (EpMab-16) exerts anti-tumor activity against oral squamous cell carcinomas
Oncol Rep., 44(6), 2517-2526, https://doi.org/10.3892/or.2020.7808, 2020 (PDF)
37. Hosono H, Ohishi T, Takei J, Asano T, Sayama Y, Kawada M, Kaneko MK, Kato Y.*
(*corresponding author)
The anti-EpCAM monoclonal antibody EpMab-16 exerts antitumor activity in a mouse model of colorectal adenocarcinoma
Oncol Lett., 20: 383, https://www.spandidos-publications.com/10.3892/ol.2020.12246, 2020 (PDF)
36. Kaneko MK, Ohishi T, Nakamura T, Inoue H, Takei J, Sano M, Asano T, Sayama Y, Hosono H, Suzuki H, Kawada M, Kato Y.*
(*corresponding author)
Development of Core-fucose Deficient Humanized and Chimeric Anti-Human Podoplanin Antibodies
Monoclon. Antib. Immunodiagn. Immunother., 39(5), 167–174, https://doi.org/10.1089/mab.2020.0019, 2020 (PDF)
35. Ogasawara S, Suzuki K, Naruchi K, Nakamura S, Shimabukuro J, Tsukahara N, Kaneko MK, Kato Y, Murata T.
Crystal structure of an anti-podoplanin antibody bound to a disialylated O-linked glycopeptide
Biochem Biophys Res Commun., 533(1), 57-63, https://doi.org/10.1016/j.bbrc.2020.08.103, 2020 (PDF)
34. Kaneko MK, Ohishi T, Kawada M, Kato Y.
A cancer-specific anti-podocalyxin monoclonal antibody (60-mG2a-f) exerts antitumor effects in mouse xenograft models of pancreatic carcinoma
Biochem Biophys Rep., 24, 100826, https://doi.org/10.1016/j.bbrep.2020.100826, 2020 (PDF)
33. Takei J, Kaneko MK, Ohishi T, Hosono H, Nakamura T, Yanaka M, Sano M, Asano T, Sayama Y, Kawada M, Harada H, Kato Y.*
(*corresponding author)
A defucosylated anti-CD44 monoclonal antibody 5-mG2a-f exerts antitumor effects in mouse xenograft models of oral squamous cell carcinoma
Oncol Rep., 44: 1949-1960, https://doi.org/10.3892/or.2020.7735 (PDF)
32. Miura K, Yoshida H, Nosaki S, Kaneko MK, Kato Y.
RAP tag and PMab-2 antibody: a tagging system for detecting and purifying proteins in plant cells
Front. Plant Sci.,11, 510444, doi: 10.3389/fpls.2020.510444, 2020 (PDF)
31. Sano M, Asano T, Kaneko MK, Kato Y.*
(*corresponding author)
Epitope mapping of an anti-diacylglycerol kinase delta monoclonal antibody DdMab-1
Biochem Biophys Rep., 24, 100808, https://doi.org/10.1016/j.bbrep.2020.100808, 2020 (PDF)
30. Takei J, Ohishi T, Kaneko MK, Harada H, Kawada M, Kato Y.*
(*corresponding author)
A defucosylated anti-PD-L1 monoclonal antibody 13-mG2a-f exerts antitumor effects in mouse xenograft models of oral squamous cell carcinoma
Biochem Biophys Rep.,, 24, 100801, https://doi.org/10.1016/j.bbrep.2020.100801, 2020 (PDF)
29. Kaneko MK, Sano M, Takei J, Asano T, Sayama Y, Hosono H, Kobayashi A, Konnai S, Kato Y*
(*corresponding author)
Development and Characterization of Anti-Sheep Podoplanin Monoclonal Antibodies PMab-253 and PMab-260
Monoclon. Antib. Immunodiagn. Immunother., 39(4):144–155 DOI: 10.1089/mab.2020.0018, 2020 (PDF)
28. Furusawa Y, Kaneko MK, Kato Y*
(*corresponding author)
Establishment of an Anti-CD20 Monoclonal Antibody (C20Mab-60) for Immunohistochemical Analyses
Monoclon. Antib. Immunodiagn. Immunother.,39(4):112–116, DOI: 10.1089/mab.2020.0015, 2020 (PDF)
27. Kato Y*, Ohishi T, Takei J, Nakamura T, Kawada M, Kaneko MK.
(*corresponding author)
An anti-human epidermal growth factor receptor 2 monoclonal antibody (H2Mab-19) exerts antitumor activity in glioblastoma xenograft models
Monoclon. Antib. Immunodiagn. Immunother.,39(4):135–139, https://doi.org/10.1089/mab.2020.0013, 2020 (PDF)
26.Sano M, Kaneko MK, Kato Y.*
(*corresponding author)
Epitope mapping of DhMab-1, an anti-diacylglycerol kinase monoclonal antibody
Monoclon. Antib. Immunodiagn. Immunother.,39(4):140–143, https://doi.org/10.1089/mab.2020.0014, 2020 (PDF)
25. Kato Y*, Ohishi T, Takei J, Nakamura T, Sano M, Asano T, Sayama Y, Hosono H, Kawada M, Kaneko MK.
(*corresponding author)
An anti-human epidermal growth factor receptor 2 monoclonal antibody H2Mab-19 exerts antitumor activity in mouse colon cancer xenografts
Monoclon. Antib. Immunodiagn. Immunother.,39(4):123–128, doi:10.1089/mab.2020.0009, 2020 (PDF)
24. Asano T, Sano M, Takei J, Sayama Y, Kaneko MK, Kato Y*
(*corresponding author)
Epitope mapping of the anti-diacylglycerol kinase monoclonal antibody DhMab-4 for immunohistochemical analysis
Monoclon. Antib. Immunodiagn. Immunother.,39(4):117–122, DOI: 10.1089/mab.2020.0012, 2020 (PDF)
23. Tomokazu Ohishi, Yukinari Kato, Mika K. Kaneko, Shun-ichi Ohba, Hiroyuki Inoue, Akiko Harakawa, Manabu Kawada.
Anti-metastatic activity of an anti-EGFR monoclonal antibody against metastatic colorectal cancer with KRAS p.G13D mutation.
Int. J. Mol. Sci., 21(17), 6037; https://doi.org/10.3390/ijms21176037, 2020 (PDF)
22. Hideki Hosono, Junko Takei, Tomokazu Ohishi, Masato Sano, Teizo Asano, Yusuke Sayama, Takuro Nakamura, Miyuki Yanaka, Manabu Kawada, Hiroyuki Harada, Mika Kato Kaneko, Yukinari Kato*
(*corresponding author)
The anti-EGFR monoclonal antibody 134-mG2a exerts antitumor effects in mouse xenograft models of oral squamous cell carcinoma
International Journal of Molecular Medicine, 46(4), 1443-1452, 2020, https://doi.org/10.3892/ijmm.2020.4700 (PDF)
21. Asano T, Kaneko MK, Kato Y.*
(*corresponding author)
RIEDL tag: A novel pentapeptide tagging system for transmembrane protein purification
Biochem Biophys Rep., 23, 100780; https://doi.org/10.1016/j.bbrep.2020.100780, 2020 (PDF)
20. Kato Y*, Sano M, Asano T, Sayama Y, Kaneko MK.
(*corresponding author)
Thr80 of sheep podoplanin is a critical epitope of the anti-sheep podoplanin monoclonal antibody, PMab-256
Monoclon. Antib. Immunodiagn. Immunother., 39(3):95–100, https://doi.org/10.1089/mab.2020.0010, 2020 (PDF)
19. Kato Y*, Ohishi T, Sano M, Asano T, Sayama Y, Takei J, Kawada M, Kaneko MK.
(*corresponding author)
H2Mab-19 anti-human epidermal growth factor receptor 2 monoclonal antibody therapy exerts antitumor activity in pancreatic cancer xenograft models
Monoclon. Antib. Immunodiagn. Immunother., 39(3):61–65; , https://doi.org/10.1089/mab.2020.0011, 2020 (PDF)
18. Kato Y*, Takei J, Sano M, Asano T, Sayama Y, Uchida K, Nakagawa T, Kaneko MK.
(*corresponding author)
Detection of lion podoplanin using the anti-tiger podoplanin monoclonal antibody PMab-231
Monoclon. Antib. Immunodiagn. Immunother., 39(3):91–94; , https://doi.org/10.1089/mab.2020.0008, 2020 (PDF)
17. Kato Y*, Furusawa Y, Sano M, Takei J, Nakamura T, Yanaka M, Okamoto S, Handa S, Komatsu Y, Asano T, Sayama Y, Kaneko MK.
(*corresponding author)
Development of an Anti-Sheep Podoplanin Monoclonal Antibody PMab-256 for Immunohistochemical Analysis of Lymphatic Endothelial Cells
Monoclon. Antib. Immunodiagn. Immunother., 39(3):82–90; DOI: 10.1089/mab.2020.0005, 2020 (PDF)
16. Sayama Y, Sano M, Asano T, Furusawa Y, Takei J, Nakamura T, Yanaka M, Okamoto S, Handa S, Komatsu Y, Nakamura Y, Yanagawa M, Kaneko MK, Kato Y.*
(*corresponding author)
Epitope mapping of PMab-241, a lymphatic endothelial cell-specific anti-bear podoplanin monoclonal antibody
Monoclon. Antib. Immunodiagn. Immunother., 39(3):77–81; DOI: 10.1089/mab.2020.0004, 2020 (PDF)
15. Mukai C, Choi E, Sams KL, Klampen EZ, Anguish L, Marks BA, Rice EJ, Wang Z, Choate LA, Chou SP, Kato Y, Miller AD, Danko CG, Coonrod SA.
Chromatin run-on sequencing analysis finds that ECM remodeling plays an important role in canine hemangiosarcoma pathogenesis
BMC Veterinary Research, 16:206, DOI: 10.1186/s12917-020-02395-3, 2020 (PDF)
14. Furusawa Y, Kaneko MK, Kato Y.*
(*corresponding author)
Establishment of C20Mab-11, a novel anti-CD20 monoclonal antibody, for the detection of B cells
Oncol Lett., 20(2), 1961-1967; https://doi.org/10.3892/ol.2020.11753, 2020 (PDF)
13. Junko Takei, Mika K. Kaneko, Tomokazu Ohishi, Manabu Kawada, Hiroyuki Harada, Yukinari Kato*
(*corresponding author)
H2Mab-19, an anti-human epidermal growth factor receptor 2 monoclonal antibody exerts antitumor activity in mouse oral cancer xenografts
Exp Ther Med., 20: 846-853, https://doi.org/10.3892/etm.2020.8765, 2020 (PDF)
12. Shinada M, Kato D, Kamoto S, Yoshimoto S, Tsuboi M, Yoshitake R, Eto S, Ikeda N, Saeki K, Hashimoto Y, Takahashi Y, Chambers J, Uchida K, Kaneko MK, Fujita N, Nishimura R, Kato Y, Nakagawa T.
PDPN is expressed in various types of canine tumors and its silencing induces apoptosis and cell cycle arrest in canine malignant melanoma
Cells, 9(5):E1136. doi: 10.3390/cells9051136., 2020 (PDF)
11. Nishinaga Y, Sato K, Yasui H, Taki S, Takahashi K, Shimizu M, Endo R, Koike C, Kuramoto N, Nakamura S, Fukui T, Yukawa H, Baba Y, K Kaneko M, Chen-Yoshikawa TF, Kobayashi H, Kato Y, Hasegawa Y.
Targeted Phototherapy for Malignant Pleural Mesothelioma: Near-Infrared Photoimmunotherapy Targeting Podoplanin
Cells,9(4), 1019; https://doi.org/10.3390/cells9041019, 2020 (PDF)
10. Kato Y*, Ito Y, Ohishi T, Kawada M, Nakamura T, Sayama Y, Sano M, Asano T, Yanaka M, Okamoto S, Handa S, Komatsu Y, Takei J, Kaneko MK.
(*corresponding author)
Antibody–drug conjugates using mouse–canine chimeric anti-dog podoplanin antibody exerts antitumor activity in a mouse xenograft model
Monoclon. Antib. Immunodiagn. Immunother., 39(2); 37-44; https://doi.org/10.1089/mab.2020.0001, 2020 (PDF)
9. Yamada S, Kaneko MK, Sayama Y, Asano T, Sano M, Yanaka M, Nakamura T, Okamoto S, Handa S, Komatsu Y, Nakamura Y, Furusawa Y, Takei J, Kato Y.*
(*corresponding author)
Development of novel mouse monoclonal antibodies against human CD19
Monoclon. Antib. Immunodiagn. Immunother., 39(2);45-50; DOI: 10.1089/mab.2020.0003, 2020 (PDF)
8. Kuwata T, Yoneda K, Mori M, Kanayama M, Kuroda K, Kaneko MK, Kato Y, Tanaka F.
Effective detection of circulating tumor cells (CTCs) in malignant pleural mesothelioma (MPM) with the "universal" CTC-chip and an anti-podoplanin antibody NZ-1.2
Cells, 9(4), 888; https://doi.org/10.3390/cells9040888, 2020 (PDF)
7. Takei J, Kaneko MK, Ohishi T, Kawada M, Harada H, Kato Y.*
(*corresponding author)
A novel anti-EGFR monoclonal antibody (EMab-17) exerts antitumor activity against oral squamous cell carcinomas via antibody-dependent cellular cytotoxicity and complement-dependent cytotoxicity
Oncol Lett., 19(4), 2809-2816, https://doi.org/10.3892/ol.2020.11384, 2020, (PDF)
6. Sayama Y, Sano M, Kaneko MK, Kato Y*
(*corresponding author)
Epitope analysis of an anti-whale podoplanin monoclonal antibody, PMab-237, using flow cytometry
Monoclon. Antib. Immunodiagn. Immunother., 39(1):17-22, https://doi.org/10.1089/mab.2019.0045, 2020, (PDF)
2019
5. Sayama Y, Sano M, Furusawa Y, Kaneko MK, Kato Y*
(*corresponding author)
Epitope Mapping of PMab-225 an Anti-Alpaca Podoplanin Monoclonal Antibody using Flow Cytometry
Monoclon. Antib. Immunodiagn. Immunother., 38(6):255–260, DOI: 10.1089/mab.2019.0033, 2019 (PDF)
4. Takei J, Yamada S, Konnai S, Ishinazaka T, Shimozuru M, Kaneko MK, Kato Y.*
(*corresponding author)
PMab-241 Specifically Detects Bear Podoplanin of Lymphatic endothelial cells in the Lung of Brown Bear
Monoclon. Antib. Immunodiagn. Immunother., 38(6):282–284, https://doi.org/10.1089/mab.2019.0038, 2019 (PDF)
3. Kaneko MK, Sayama Y, Sano M, Kato Y.*
(*corresponding author)
The Epitope of PMab-210 is Located in Platelet Aggregation-Stimulating Domain-3 of Pig Podoplanin
Monoclon. Antib. Immunodiagn. Immunother.,38(6):271–276, https://doi.org/10.1089/mab.2019.0037, 2019 (PDF)
2. Kato Y*, Sayama Y, Sano M, Kaneko MK.
(*corresponding author)
Epitope Analysis of an Anti-Horse Podoplanin Monoclonal Antibody PMab-219
Monoclon. Antib. Immunodiagn. Immunother.,38(6):266–270 https://doi.org/10.1089/mab.2019.0034, 2019 (PDF)
1. Sano M, Kaneko MK, Kato Y.*
(*corresponding author)
Epitope Mapping of Monoclonal Antibody PMab-233 Against Tasmanian Devil Podoplanin
Monoclon. Antib. Immunodiagn. Immunother.,38(6): 261–265, DOI: 10.1089/mab.2019.0032, 2019 (PDF)