Glycan array analysis of Pholiota squarrosa lectin (PhoSL) and other fucose-oriented lectins
LC Rubén, MR Laura, FB Almudena, GM Emilio - Glycobiology, 2020
Abstract The α (1, 6) fucose residue attached to the N-glycoprotein core is suspected
to play an essential role in the progression of several types of cancer. Lectins remain
the first choice for probing glycan modifications, although they may lack specificity …
to play an essential role in the progression of several types of cancer. Lectins remain
the first choice for probing glycan modifications, although they may lack specificity …
• | 引用: Anti-podocalyxin antibody exerts antitumor effects via … |
[PDF] Avaliação do budding tumoral em biópsias incisionais de carcinoma epidermóide de boca e sua associação com a expressão imuno-histoquímica das proteínas …
PV Kammer - 2020
O budding tumoral (BT) é um marcador morfológico associado a perda de adesão
celular, invasão tumoral e possivelmente a transição epitélio-mesenquimal. As
proteínas podoplanina e osteopontina são biomarcadores associados ao …
celular, invasão tumoral e possivelmente a transição epitélio-mesenquimal. As
proteínas podoplanina e osteopontina são biomarcadores associados ao …
• | 引用: Podoplanin emerges as a functionally relevant oral cancer … |
[HTML] Transcriptional regulation of memory B cell differentiation
BJ Laidlaw, JG Cyster - Nature Reviews Immunology, 2020
Memory B cells (MBCs) are critical for the rapid development of protective immunity
following re-infection. MBCs capable of neutralizing distinct subclasses of
pathogens, such as influenza and HIV, have been identified in humans. However …
following re-infection. MBCs capable of neutralizing distinct subclasses of
pathogens, such as influenza and HIV, have been identified in humans. However …
• | 引用: The mTOR-Bach2 cascade controls cell cycle and class … |
[HTML] Identification of Targets to Redirect CAR T Cells in Glioblastoma and Colorectal Cancer: An Arduous Venture
E Ponterio, R De Maria, TL Haas - Frontiers in Immunology, 2020
The chimeric antigen receptor (CAR) is an artificial molecule engineered to induce
cytolytic T cell reactions in tumors. Generally, this molecule combines an
extracellular single-chain variable fragment (scFv) able to recognize tumor …
cytolytic T cell reactions in tumors. Generally, this molecule combines an
extracellular single-chain variable fragment (scFv) able to recognize tumor …
• | 引用: Antiglycopeptide mouse monoclonal antibody LpMab-21 … |
FoxP3, CTLA-4, and IDO in Canine Melanocytic Tumors
I Porcellato, C Brachelente, K Cappelli, L Menchetti… - Veterinary Pathology, 2020
Despite promising immunotherapy strategies in human melanoma, there are few
studies on the immune environment of canine melanocytic tumors. In humans, the
activation of immunosuppressive cell subpopulations, such as regulatory T cells …
studies on the immune environment of canine melanocytic tumors. In humans, the
activation of immunosuppressive cell subpopulations, such as regulatory T cells …
• | 引用: A canine chimeric monoclonal antibody targeting PD-L1 and … |
[PDF] Analysis of the impact of Colony Stimulating Factor (CSF)-1 administration in adult rats using a novel
KM Irvine, M Caruso, MF Cestari, GM Davis, S Keshvari…
Macrophages are present in large numbers in every tissue in the body where they
play critical roles in development and homeostasis. They exhibit remarkable
phenotypic and functional diversity, underpinning their adaptation to specialized …
play critical roles in development and homeostasis. They exhibit remarkable
phenotypic and functional diversity, underpinning their adaptation to specialized …
• | 引用: Development and characterization of a novel Prox1-EGFP … |
Matrix metalloproteinase MMP1 and MMP9 genes expression in breast cancer tissue
H Mohammadian, R Sharifi, SR Amirdehi, E Taheri… - Gene Reports, 2020
Nowadays, Breast cancer is recognized as the most common cancer among women
worldwide. Matrix metalloproteinases (MMPs) are a group of endopeptidase
enzymes that can degrade extracellular matrix proteins and increase invasion and …
worldwide. Matrix metalloproteinases (MMPs) are a group of endopeptidase
enzymes that can degrade extracellular matrix proteins and increase invasion and …
• | 引用: The role of MMP-1 in breast cancer growth and metastasis to … |