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Allergic reactions to penicillin family antibiotics commonly result in skin-related symptoms, such as rash, hives and itching. In some cases, severe allergic reactions can lead to anaphylaxis, which can cause difficulty breathing, abdominal pain, dizziness, fever and/or abnormal heart rhythm. Allergic reactions are potentially serious complications that may require immediate medical care. For in-depth information about potential side effects of amoxicillin treatment, refer to the physician’s insert or consult a medical professional. For more information about contraindications in general, refer to Avoiding Negative Drug Interactions. Children at increased risk for pneumococcal infections should receive pneumococcal 7-valent conjugate vaccine and pneumococcal 23-valent polysaccharide vaccine. Long-term anti-infective prophylaxis recommended for children with functional or anatomic asplenia regardless of vaccination status. Usual Pediatric Dose for Pneumonia. 40 to 50 mg/kg/day orally in divided doses every 8 hours. Usual Pediatric Dose for Tonsillitis/Pharyngitis. 4 weeks to 3 months: 20 to 30 mg/kg/day in divided doses every 12 hours. 4 months to 12 years: 20 to 50 mg/kg/day in divided doses every 8 to 12 hour. 12 years or older: Immediate-release: 250 to 500 mg orally 3 times a day for 7 to 10 days; alternatively, 500 to 875 mg orally twice a day may be administered Elimination Route. Eliminated principally in urine by both glomerular filtration and tubular secretion. Approximately 50–80% of amoxicillin dose excreted unchanged in urine. Half-life. 1–1.4 hours.- amoxicillin clavulan
