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An alternative for postexposure prophylaxis of anthrax following exposure to aerosolized Bacillus anthracis spores (inhalational anthrax). Ciprofloxacin or doxycycline are initial drugs of choice for postexposure prophylaxis following a suspected or confirmed bioterrorism-related anthrax exposure. If penicillin susceptibility is confirmed, consideration can be given to changing prophylaxis to a penicillin in infants and children and in pregnant or lactating women; amoxicillin usually recommended. For certain types of difficult-to-treat infections, your doctor may prescribe these 2 medications together in order to achieve this effect. Consult your doctor or pharmacist for more details. Although most antibiotics probably do not affect hormonal birth control such as pills, patch, or ring, some antibiotics may decrease their effectiveness. Usual Pediatric Dose for Bacterial Endocarditis Prophylaxis. 50 mg/kg orally as a single dose 1 hour prior to procedure. Amoxicillin is not appropriate as endocarditis prophylaxis for patients identified as high-risk, including those with prosthetic heart valves, prior endocarditis, and those who have had surgically constructed systemic shunts or conduits. These patients should receive appropriate parenteral antimicrobial therapy. Usual Pediatric Dose for Anthrax Prophylaxis. 80 mg/kg/day divided into equal doses administered orally every 8 hours. Maximum dose: 500 mg/dose.- amoxicillin for impetigo
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