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The routes to many important outcomes including diseases and ultimately death as well as financial credit consist of multiple complex pathways containing interrelated events and conditions. We have historically lacked effective methodologies for identifying these pathways and their non-linear and interacting features. This book focuses on recursive partitioning strategies as a response to the challenge of pathway characterisation. A highlight of the second edition is the many worked examples, most of them from epidemiology, bioinformatics, molecular genetics, physiology, social demography, banking, and marketing. The statistical issues, conceptual and computational, are not only treated in detail in the context of important scientific questions, but also an array of substantively-driven judgements are explicitly integrated in the presentation of examples. Going considerably beyond the standard treatments of recursive partitioning that focus on pathway representations via single
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