Rami-Abdul-Rahman, who heads the Britain-based Syrian Observatory for Human Rights, said Saturday rebels took over two army posts on the road near Aleppo after days of fighting.
The regime built the desert road as a backup route after rebels captured the town of Maaret al-Numan in October cutting the main highway between the country's two largest cities.
The Observatory also reported clashes in the town of Qusair, near the border with Lebanon.
The fighting in the town came a day after U.N. commissioner for human rights Navi Pillay expessed alarm over Qusair, which has been besieged by Syrian troops for several weeks.
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