That means international markets could shape regional trading and Japanese stocks are up due to a positive overnight lead from Wall Street and steady oil prices.
Fed chairman Ben Bernanke has the opportunity to soothe market jitters about a possible scaling back of the bank's $85 billion monthly bond-purchase programme.
The quantitative easing policy has helped fuel a global rally in stock markets and recent talk of a pullback in stimulus has knocked major indexes off their highs.
Regional markets, especially those in United Arab Emirates, Qatar, Oman and Saudi Arabia have rallied in recent months as strengthening local fundamentals boosted sentiment. But while U.S. equities have recovered sharp losses triggered by the 2008 financial crisis, regional markets continue to lag from a long-term perspective.
Change to U.S. monetary policy could affect global sentiment and subsequently Gulf market confidence.
In the UAE, Dubai's index has traded within a range of about 130 points following an early-year surge, with investors now looking for new positive catalysts to justify further gains or a correction to buy at lower prices.
It slipped 0.1 percent to 2,379 points on Tuesday, trimming 2013 gains to 46.7 percent.
"A medium-to-high probability entry signal to go 'long' will be given with the upward break of 2,430 after the market found support at 2,320," MENA Corp says in a note. "Only the downward break of 2,320 would cancel the bullish scenario."
In Kuwait, mobile operator Zain will be in focus after its chief executive told Reuters the firm will make acquisitions and partnerships in computer-based industries this year to exploit rising demand for data and help offset falling conventional call and text income. (Reporting by Nadia Saleem; Editing by Matt Smith)
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