骨粗鬆症女性の骨密度に対する振動療法の効果
閉経後の骨粗鬆症女性の骨密度に対する振動療法の効果のリサーチThe National Library of Medicine (NLM)2008年に発表されたもの。背景:この研究の目的は、非侵襲的で機械的に媒介される振動が、閉経後の骨ミネラル密度 (BMD) の低下を抑制し、腰椎と大腿骨頸部の BMD を高め、閉経後の骨粗鬆症の女性の慢性的な背中の痛みを軽減するかどうかを判断すること。方法:合計 116 人の閉経後の骨粗鬆症の女性がこの研究に参加し、グループ A (66 人の患者) とグループ B (50 人の患者) に分けられた。グループ A は振動治療を受診被験者は、振動数 30 Hz、振幅 5 mm の振動プラットフォームを使用週に 5 回、毎回 10 分間、合計で 6 か月間治療を受けた)。グループ B は、何も処理せずにコントロールとして機能。L2 - 4 BMD、両側大腿骨頸部 BMD、およびボディマス指数 (BMI) は、治療前または治療の 3 か月目と 6 か月目にそれぞれ記録された。治療終了後、各群のBMDの変化を比較・分析した。慢性腰痛は、ベースラインと治療の 3 か月目と 6 か月目に視覚的アナログ スケール (VAS) によって評価。結果:116 人の女性のうち、グループ A の 51 人の女性 ((61.23 +/- 8.20) 歳) とグループ B の 43 人の女性 ((63.73 +/- 5.45) 歳) の94 人が研究を完了。年齢、BMI、閉経年数、腰椎 BMD、大腿骨頸部 BMD、および VAS を含むベースライン特性に 2 つのグループ間で有意差なし。腰椎 BMDグループ A の 51 人の女性： 3 か月の振動治療後に 1.3% (P = 0.034) 増加し、 6 か月目には 4.3% (P = 0.000) 増加した。グループ B の43人の女性： 3 か月目に減少したが、統計的有意性はなし (P > 0.05)。 6 か月目には、1.9% 減少 (P < 0.05)。大腿骨頸部 BMDグループ A： 3 か月の振動治療後にわずかに増加したが、統計的有意性はなし (P > 0.05)。 6 か月目に、BMD は 3.2% 増加 (P < 0.05)。グループ B： 3 か月目には有意に減少なしだが (P = 0.185)、 6 か月目には有意に減少しました (1.7%) (P < 0.05)。慢性腰痛 (VAS) は、ベースラインと比較して、振動療法後 3 か月目と 6 か月目 (P < 0.05) にグループ A でより有意に減少し。BMI は、追跡期間中に 2 つのグループで大幅に変更されなかった。結論:振動療法は、骨粗鬆症の閉経後の女性の慢性的な背中の痛みを軽減し、大腿骨頸部と腰部の BMD を増加させるのに効果的。https://pubmed.ncbi.nlm.nih.gov/18710630/National Library of MedicineThe National Library of Medicine (NLM) is a leader in research in biomedical informatics and data science and the world’s largest biomedical library. NLM conducts and supports research in methods for recording, storing, retrieving, preserving, and communicating health information. It is part of the National Institutes of Health (NIH).Xiang-Yan Ruan 1、Feng-Yu Jin、Yu-Lan Liu、Zhou-Li Peng、Yun-Gao SunPMID: 18710630Effects of vibration therapy on bone mineral density in postmenopausal women with osteoporosisXiang-Yan Ruan 1, Feng-Yu Jin, Yu-Lan Liu, Zhou-Li Peng, Yun-Gao SunAffiliations expandPMID: 18710630Abstract：Background: Jaw osteonecrosis possibly associated with the administration of bisphosphonates is expected to be treated with a non-pharmacologic approach. This study aimed to determine whether noninvasive, mechanically mediated vibration would inhibit the decline in bone mineral density (BMD) that follows menopause, enhance the BMD of the lumbar and femoral neck, and reduce chronic back pain in postmenopausal women with osteoporosis.Methods:A total of 116 postmenopausal women with osteoporosis participated in this study, and they were divided into groups A (66 patients) and B (50). Group A received vibration treatment (Subjects vertically stand on the vibration platform, with a vibration frequency of 30 Hz, amplitude of 5 mm; they received the treatment five times per week, ten minutes each time and totally for six months), whereas women of group B served as controls without any treatment. L2 - 4 BMD, bilateral femoral neck BMD, and body mass index (BMI) were recorded before the treatment or at the third and sixth months of the treatment respectively. After the ending of the treatment, the change of BMD in each group was compared and analyzed. Chronic back pain was evaluated by visual analogue scale (VAS) at baseline and the third and sixth months of the treatment.Results:Of the 116 women, 94 including 51 women from group A ((61.23 +/- 8.20) years) and 43 women from group B ((63.73 +/- 5.45) years), completed the study. There were no significant differences in baseline characteristics including age, BMI, menopausal years, lumbar BMD, femoral neck BMD, and VAS between the two groups. The lumbar BMD of the 51 women in group A increased by 1.3% (P = 0.034) after vibration treatment for 3 months and by 4.3% at the sixth month (P = 0.000). The lumbar BMD in group B was decreased at the third month, but there was not statistical significance (P > 0.05). At the sixth month, it was decreased by 1.9% (P < 0.05). The femoral neck BMD of the 51 women in group A was slightly increased after vibration treatment for 3 months, but without statistical significance (P > 0.05). At the sixth month, the BMD was increased by 3.2% (P < 0.05). In group B, the BMD was not decreased significantly (P = 0.185) at the third month, but decreased significantly at the sixth month (1.7%) (P < 0.05) compared with the baseline. Chronic back pain (VAS) reduced more significantly in group A at the third and the sixth months (P < 0.05) after vibration therapy in comparison with the baseline. The BMI was not significantly changed in the two groups during the period of follow-up.Conclusions:Vibration therapy appears to be useful in reducing chronic back pain and increasing the femoral neck and lumbar BMD in postmenopausal women with osteoporosis.
