The resistance of body's cells to insulin is a major problem faced by patients with type Ⅱdiabetes . The patient's body not only can not make a good use of its own secreted insulin , but also due to elevated blood glucose, the body's pancreatic β cells will try its efforts to secrete more insulin , leading to insulin metabolism disorders , finally resulting the failure of pancreatic β cells , eventually they will loss function of insulin secretion .
MiR-7 is a micro RNA molecule in the human body , there are about 700 kinds of micro-RNA molecules which play an important role in regulate human cell function .Responsible for the study, ETH Zurich Professor Markus Shituofeier said, miR-7 can be used as a biological marker for the early diagnosis of diabetes, the future can be developed for miR-7 inhibitor class of drugs for the treatment of ⅱ diabetes. Researchers researched on mice and humans , finding that the higher concentration of miR-7 small RNA molecules , the bigger inhibiting effects on pancreatic β cells secrete insulin . Besides , the researchers also found that when the concentration of miR-7 RNA stays in a higher state , pancreatic β cells may miss part function of insulin secretion .
The researchers also claimed that , miR-7 can be considered as a biomarker for the detection of early diabetes . And in the future , a series of inhibitor drugs target to miR-7 can be developed to treat type II diabetes .Bioabb is a professional biotechnology company , specialized in high quality antibody production and custom service . Bioabb now produced about 5000 antibodies , including monoclonal antibody , polyclonal antibody , secondary antibody , diagnostic antibody and so on . Bioabb antibodies are widely used in biology research fields , besides , they also provide strong support for modern medicine .
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