Patient Needs: A Communication Map
E Gil Deza - Improving Clinical Communication: A Clinician's Guide …, 2024
There are specific communication situations in which communication is more rigid
and limited, such as emergency situations, especially in large disasters. All
communication must be focused on saving lives and is, or should be, centralized to
avoid confusion and overlapping efforts. These situations are all guided by protocols
and we will analyze the most relevant ones. However, when it comes to chronic
diseases, there is much less protocol, not because they are less frequent, but …
and limited, such as emergency situations, especially in large disasters. All
communication must be focused on saving lives and is, or should be, centralized to
avoid confusion and overlapping efforts. These situations are all guided by protocols
and we will analyze the most relevant ones. However, when it comes to chronic
diseases, there is much less protocol, not because they are less frequent, but …
| • | 引用: Current targeted therapy for metastatic colorectal cancer  |
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[HTML] Ferroptosis regulation by Cap'n'collar family transcription factors
MB Murray, SJ Dixon - Journal of Biological Chemistry, 2024
Ferroptosis is an iron-dependent cell death mechanism that may be important to
prevent tumor formation and useful as a target for new cancer therapies.
Transcriptional networks play a crucial role in shaping ferroptosis sensitivity by
regulating the expression of transporters, metabolic enzymes, and other proteins.
The Cap'n'collar (CNC) protein nuclear factor erythroid 2 like 2 (NFE2L2, also known
as NRF2) is a key regulator of ferroptosis in many cells and contexts. Emerging …
prevent tumor formation and useful as a target for new cancer therapies.
Transcriptional networks play a crucial role in shaping ferroptosis sensitivity by
regulating the expression of transporters, metabolic enzymes, and other proteins.
The Cap'n'collar (CNC) protein nuclear factor erythroid 2 like 2 (NFE2L2, also known
as NRF2) is a key regulator of ferroptosis in many cells and contexts. Emerging …
| • | 引用: BACH1 promotes pancreatic cancer metastasis by repressing … |
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Remifentanil represses oxidative stress to relieve hepatic ischemia/reperfusion injury via regulating BACH1/PRDX1 axis
Y You, S Chen, H Deng, X Xing, B Tang, Y Wu, E Lei - Clinics and Research in …, 2024
Background: Hepatic ischemia-reperfusion injury (HIRI) is a major cause of liver
dysfunction after clinical liver surgery, which seriously affects the prognosis of
patients. Remifentanil (RE) has been verified to attenuate HIRI. However, its
therapeutic mechanism is still unclear. This study aimed to explore the protective
mechanism of RE against HIRI. Methods: A mouse HIRI model and an in vitro model
of hypoxia/reoxygenation (H/R)-stimulated AML12 hepatocytes were established …
dysfunction after clinical liver surgery, which seriously affects the prognosis of
patients. Remifentanil (RE) has been verified to attenuate HIRI. However, its
therapeutic mechanism is still unclear. This study aimed to explore the protective
mechanism of RE against HIRI. Methods: A mouse HIRI model and an in vitro model
of hypoxia/reoxygenation (H/R)-stimulated AML12 hepatocytes were established …
| • | 引用: BACH1 promotes pancreatic cancer metastasis by repressing … |